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Immunity
Virologie

mRNA vaccination of naive and COVID-19-recovered individuals elicits potent memory B cells that recognize SARS-CoV-2 variants

Immunity
Immunologie

A subset of Kupffer cells regulates metabolism through the expression of CD36

Cancer Research
Onkologie

Allosteric inhibition of HER2 by Moesin-mimicking compounds targets HER2-positive cancers and brain metastases

JID innovations
Stoffwechselkrankheiten

Deletion of TNFAIP6 Gene in Human Keratinocytes Demonstrates a Role for TSG-6 to Retain Hyaluronan Inside Epidermis

PNAS
Stoffwechselkrankheiten

Arrest of WNT/β-catenin signaling enables the transition from pluripotent to differentiated germ cells in mouse ovaries

Cancers (Basel)
Onkologie

Mitochondrial Metabolism in Carcinogenesis and Cancer Therapy

Cardiovascular research
Stoffwechselkrankheiten

Different cardiovascular and pulmonary phenotypes for single- and double-knock-out mice deficient in BMP9 and BMP10

Blood.
Onkologie

GlcNAc is a mast-cell chromatin-remodeling oncometabolite that promotes systemic mastocytosis aggressiveness

JCI Insight
Molekularbiologie

Phosphatase inhibition by LB-100 enhances BMN-111 stimulation of bone growth

Cells
Onkologie

Microtubule-Associated Protein ATIP3, an Emerging Target for Personalized Medicine in Breast Cancer

Oncoimmunology
Onkologie

Tumor spread or siege immunity: dissemination to distant metastasis or not

Science Advances
Immunologie

Agonist anti-ChemR23 mAb reduces tissue neutrophil accumulation and triggers chronic inflammation resolution