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Molecular therapy
Biologie moléculaire

A combinatorial EV-miRNA signature mediates the anti-tumoral activity of NFAT3-regulated extracellular vesicles in aggressive cancers

Thrombosis and Haemostasis
Hématologie

Anti-TFPI Single-Domain Antibodies: Novel Rebalancing Therapies for Hemophilia and Other Rare Bleeding Disorders

JCI Insight
Immunologie

CD8+ T cell activation occurs 24 hours after AAV administration and is driven by muscle promoter specificity

Journal of Experimental Medicine
Immunologie

Basophils drive the resolution and promote wound healing in adult and aged mice

Circulation: Heart Failure
Maladies cardio-vasculaires

Simtuzumab Attenuates Loxl2-Mediated Extracellular Matrix Remodeling and Preserves Cardiac Function in LMNA Mutation-Induced Dilated Cardiomyopathy

Scientific Reports
Immunologie

Blood MMP-7 and TNF-α levels as potential prognostic biomarkers for adult pulmonary Langerhans cell histiocytosis

Cancer Cell
Bioinformatiques

Multiomic integration reveals tumoral heterogeneity of lipid dependence within lethal group 3 medulloblastoma

Acta Neuropathologica Communications
Bioinformatiques

Spatiotemporal transcriptomic mapping reveals region-specific glial activation and astrocyte shifts in epileptogenesis beyond the hippocampus

Nature communications
Neurologie

Prefrontal gamma oscillations and fear extinction learning require early postnatal interneuron-oligodendroglia communication

Commun Biol
Neurologie

The prefrontal operculum, a human-specific hub for the cognitive control of speech

American Journal of Hematology
Hématologie

Protein S Enhances the Phagocytosis of Phosphatidylserine-Exposing Erythrocytes: Implications in Sickle Cell Disease

Cell Death & Disease
Biologie moléculaire

SETDB1 is critically required for uveal melanoma growth and represents a promising therapeutic target