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Molecular therapy
Molecular Biology

A combinatorial EV-miRNA signature mediates the anti-tumoral activity of NFAT3-regulated extracellular vesicles in aggressive cancers

Cancer Cell
Bioinformatics

Multiomic integration reveals tumoral heterogeneity of lipid dependence within lethal group 3 medulloblastoma

Cell Death & Disease
Molecular Biology

SETDB1 is critically required for uveal melanoma growth and represents a promising therapeutic target

Nature communications
Molecular Biology

Sonic hedgehog medulloblastomas are dependent on Netrin-1 for survival

Biomedicines
Immunology

Targeting Aggressive Prostate Carcinoma Cells with Mesothelin-CAR-T Cells

eLife
Oncology

In vivo targeted and deterministic single-cell malignant transformation

Cancer letters
Oncology

Targeting WEE1 kinase as a therapeutic strategy in ATIP3-deficient breast cancers

J Clin Invest
Oncology

CXCL8 secreted by immature granulocytes inhibits WT hematopoiesis in chronic myelomonocytic leukemia

Brain
Oncology

GDF5 as a rejuvenating treatment for age-related neuromuscular failure

Molecular therapy
Oncology

DLK1/DIO3 locus upregulation by a β-catenin-dependent enhancer drives cell proliferation and liver tumorigenesis

Liver International
Oncology

Intrinsic cancer cell phosphoinositide 3-kinase δ regulates fibrosis and vascular development in cholangiocarcinoma

Cancers (Basel)
Oncology

A Network of 17 Microtubule-Related Genes Highlights Functional Deregulations in Breast Cancer