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Molecular therapy
Biologie moléculaire

A combinatorial EV-miRNA signature mediates the anti-tumoral activity of NFAT3-regulated extracellular vesicles in aggressive cancers

Cancer Cell
Bioinformatiques

Multiomic integration reveals tumoral heterogeneity of lipid dependence within lethal group 3 medulloblastoma

Cell Death & Disease
Biologie moléculaire

SETDB1 is critically required for uveal melanoma growth and represents a promising therapeutic target

Nature communications
Biologie moléculaire

Sonic hedgehog medulloblastomas are dependent on Netrin-1 for survival

Biomedicines
Immunologie

Targeting Aggressive Prostate Carcinoma Cells with Mesothelin-CAR-T Cells

eLife
Oncologie

In vivo targeted and deterministic single-cell malignant transformation

Cancer letters
Oncologie

Targeting WEE1 kinase as a therapeutic strategy in ATIP3-deficient breast cancers

J Clin Invest
Oncologie

CXCL8 secreted by immature granulocytes inhibits WT hematopoiesis in chronic myelomonocytic leukemia

Brain
Oncologie

GDF5 as a rejuvenating treatment for age-related neuromuscular failure

Molecular therapy
Oncologie

DLK1/DIO3 locus upregulation by a β-catenin-dependent enhancer drives cell proliferation and liver tumorigenesis

Liver International
Oncologie

Intrinsic cancer cell phosphoinositide 3-kinase δ regulates fibrosis and vascular development in cholangiocarcinoma

Cancers (Basel)
Oncologie

A Network of 17 Microtubule-Related Genes Highlights Functional Deregulations in Breast Cancer